CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
Home/Biomarker

BRAF V600E

Gene: BRAF · Type: mutation

Indications: Melanoma, Non-small cell lung cancer, Colorectal cancer, Thyroid cancer

SensitivityResistanceCIViC Context

FDA Sensitivity Assertions

DrugIndicationRecommendationFDA SourceLink
VemurafenibMelanoma, Non-small cell lung cancer, Colorectal cancer, Thyroid cancerINDICATED
FDA Label
Label
DabrafenibMelanoma, Non-small cell lung cancer, Colorectal cancer, Thyroid cancerINDICATED
FDA Label
Label
TrametinibMelanoma, Non-small cell lung cancer, Colorectal cancer, Thyroid cancerINDICATED
FDA Label
Label
EncorafenibMelanoma, Non-small cell lung cancer, Colorectal cancer, Thyroid cancerINDICATED
FDA Label
Label