CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
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Hedgehog pathway activation (basal cell carcinoma)

Gene: PTCH1/SMO · Type: mutation

Indications: Basal cell carcinoma

SensitivityResistanceCIViC Context

FDA Sensitivity Assertions

DrugIndicationRecommendationFDA SourceLink
VismodegibBasal cell carcinomaINDICATED
FDA Label
Label
SonidegibBasal cell carcinomaINDICATED
FDA Label
Label