Description
FGF3 is a member of the basic fibroblast growth factor (FGF) gene family and was first identified based on it's similarity to the mouse proto-oncogene int-2. Amplifications of this gene and the surrounding region (11q13) have been observed in various cancers including breast cancer, esophogeal cancer, melanoma, bladder cancer and hepatocellular carcinoma (HCC). Lower tumor grade and stage have been associated with FGF3 amplifications in HCC; however, this event is fairly rare in this tumor type.
Cyan = gene · Slate = variant · Green = drug · Click variant to filter table
Variants (1)
| CIViC ID | Name | HGVS | Type(s) |
|---|---|---|---|
| 630 | Amplification | transcript_amplification |