Description
The RAC1 P29S mutation is the third most common protein-coding hotspot mutation in melanomas, ocurring in 4-9%. A preclinical study has shown that this mutation confers resistance to BRAF inhibition in-vitro.
Cyan = gene · Slate = variant · Green = drug · Click variant to filter table
Variants (1)
| CIViC ID | Name | HGVS | Type(s) |
|---|---|---|---|
| 367 | P29S PRO29SER | ENST00000356142.4:c.85C>T,NC_000007.13:g.6426892C>T | missense_variant |