Variant Summary
- Also known as
- RS121913421,E746_A750DELELREA
- HGVS
- —
- Variant Type(s)
- inframe_deletion
- Evidence Items
- 3
Evidence Level Distribution
Level C: 2Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = EGFR and variant = E746_A750del.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Gefitinib | 4 |
| C | Predictive | Supports | Sensitivity/Response | Bronchiolo-alveolar Adenocarcinoma | Erlotinib | 3 |
| D | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Gefitinib | 2 |