Variant Summary
- Also known as
- RS121913444
- HGVS
- NM_005228.4:c.2582T>A,NP_005219.2:p.Leu861Gln,NC_000007.13:g.55259524T>A,ENST00000275493.2:c.2582T>A
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level C: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = EGFR and variant = L861Q.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Gefitinib | 3 |
| D | Predictive | Supports | Sensitivity/Response | High Grade Glioma | Erlotinib | 3 |