CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/G245D

G245D

CIViC ID: 1036 · Gene: TP53

Variant Summary

Also known as
RS121912656
HGVS
NC_000017.10:g.7577547C>T,NM_000546.5:c.734G>A,NP_000537.3:p.Gly245Asp,ENST00000269305.4:c.734G>A
Variant Type(s)
missense_variant
Evidence Items
1

Evidence Level Distribution

Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = TP53 and variant = G245D.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DFunctionalSupportsDominant Negative3