Variant Summary
- Also known as
- ASP281GLU,D149E,D242E
- HGVS
- NM_000546.5:c.843C>G,NP_000537.3:p.Asp281Glu,NC_000017.10:g.7577095G>C,ENST0000029305.4:c.843C>G
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = TP53 and variant = D281E.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Functional | Supports | Dominant Negative | 3 |