CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Exon 21 Mutation

Exon 21 Mutation

CIViC ID: 105 · Gene: PIK3CA

Variant Summary

Also known as
EXON 20 MUTATION
HGVS
—
Variant Type(s)
exon_variant
Evidence Items
3

Evidence Level Distribution

Level B: 3

Evidence Items

Showing CIViC evidence rows where gene = PIK3CA and variant = Exon 21 Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticSupportsBetter OutcomeBreast Cancer4
BPredictiveSupportsResistanceColorectal CancerChemotherapy,Cetuximab3
BPrognosticDoes Not SupportPoor OutcomeColorectal Cancer2