Variant Summary
- Also known as
- PHE270SER,F138S,F231S
- HGVS
- NC_000017.10:g.7577129A>G,NM_000546.5:c.809T>C,NP_000537.3:p.Phe270Ser,ENST00000269305.4:c.809T>C
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = TP53 and variant = F270S.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Functional | Does Not Support | Dominant Negative | 3 |