Variant Summary
- Also known as
- R233X,ARG233TER,RS121909219
- HGVS
- NM_000314.6:c.697C>T,NP_000305.3:p.Arg233Ter,ENST00000371953.3:c.697C>T,NC_000010.10:g.89717672C>T
- Variant Type(s)
- stop_gained,loss_of_function_variant
- Evidence Items
- 2
Evidence Level Distribution
Level B: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = PTEN and variant = R233*.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Breast Cancer | MTOR Inhibitor | 4 |
| B | Prognostic | Does Not Support | Poor Outcome | Glioblastoma | 3 |