Variant Summary
- Also known as
- LYS468GLUFS
- HGVS
- NM_000051.3:c.1402_1403delAA,NP_000042.3:p.Lys468Glufs,NC_000011.9:g.108121594_108121595delAA,ENST00000278616.4:c.1402_1403delAA,NC_000011.9:g.108121594_108121595del
- Variant Type(s)
- frameshift_variant
- Evidence Items
- 1
Evidence Level Distribution
Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = ATM and variant = K468FS.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Does Not Support | Resistance | Chronic Lymphocytic Leukemia | Doxorubicin | 2 |