Variant Summary
- HGVS
- —
- Variant Type(s)
- —
- Evidence Items
- 5
Evidence Level Distribution
Level B: 5
Evidence Items
Showing CIViC evidence rows where gene = MGMT and variant = Underexpression.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Sensitivity/Response | Glioblastoma | Temozolomide | 3 |
| B | Predictive | Supports | Sensitivity/Response | High Grade Glioma | Temozolomide | 3 |
| B | Predictive | Supports | Sensitivity/Response | Glioblastoma | Temozolomide | 3 |
| B | Predictive | Supports | Sensitivity/Response | Oligodendroglioma | Temozolomide | 2 |
| B | Predictive | Supports | Sensitivity/Response | Neuroendocrine Tumor | Temozolomide | 2 |