Variant Summary
- HGVS
- —
- Variant Type(s)
- —
- Evidence Items
- 6
Evidence Level Distribution
Level B: 6
Evidence Items
Showing CIViC evidence rows where gene = RRM1 and variant = Underexpression.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Cisplatin,Gemcitabine | 4 |
| B | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Gemcitabine | 4 |
| B | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Carboplatin,Gemcitabine | 3 |
| B | Predictive | Supports | Sensitivity/Response | Pancreatic Cancer | Gemcitabine | 3 |
| B | Predictive | Supports | Sensitivity/Response | Pancreatic Cancer | Gemcitabine | 3 |
| B | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Gemcitabine,Paclitaxel,Vinorelbine | 3 |