CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/D835V

D835V

CIViC ID: 1302 · Gene: FLT3

Variant Summary

Also known as
RS121909646,ASP835VAL
HGVS
ENST00000241453.7:c.2504A>T,NM_004119.2:c.2504A>T,NP_004110.2:p.Asp835Val,NC_000013.10:g.28592641T>A
Variant Type(s)
missense_variant
Evidence Items
8

Evidence Level Distribution

Level C: 1Level D: 7

Evidence Items

Showing CIViC evidence rows where gene = FLT3 and variant = D835V.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveDoes Not SupportSensitivity/ResponseAcute Myeloid LeukemiaQuizartinib4
DPredictiveSupportsResistanceAcute Myeloid LeukemiaTandutinib3
DPredictiveDoes Not SupportSensitivity/ResponseAcute Myeloid LeukemiaSunitinib3
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaAS602868,Tyrphostin AG 12963
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaCytarabine,Sunitinib2
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaSunitinib,Daunorubicin2
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaGilteritinib2
CPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaSunitinib0