Variant Summary
- Also known as
- LEU755PRO
- HGVS
- NP_004439.2:p.Leu755Pro,NM_004448.3:c.2263_2264delinsCC,NC_000017.13:g.37880219_37880220delinsCC,ENST00000269571.5:c.2263_2264delinsCC
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level A: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = ERBB2 and variant = L755P.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| A | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Trastuzumab Deruxtecan | 2 |
| D | Predictive | Supports | Resistance | Cancer | Lapatinib | 2 |