CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

R2327W

CIViC ID: 136 · Gene: NOTCH1

Variant Summary

Also known as
ARG2327TRP
HGVS
NM_017617.4:c.6979C>T,NP_060087.3:p.Arg2327Trp,NC_000009.11:g.139391212G>A
Variant Type(s)
missense_variant
Evidence Items
1

Evidence Level Distribution

Level B: 1

Evidence Items

Showing CIViC evidence rows where gene = NOTCH1 and variant = R2327W.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticSupportsPoor OutcomeLung Non-small Cell Carcinoma4