Variant Summary
- HGVS
- ENST00000277541.6:c.6821_6822insT,NC_000009.11:g.139391369_139391370insA
- Variant Type(s)
- plus_1_frameshift_variant
- Evidence Items
- 1
Evidence Level Distribution
Level B: 1
Evidence Items
Showing CIViC evidence rows where gene = NOTCH1 and variant = S2275FS.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Prognostic | Supports | Poor Outcome | Lung Non-small Cell Carcinoma | 4 |