Variant Summary
- Also known as
- RS78311289,LYS650GLU,K652E,LYS652GLU,TDII
- HGVS
- NC_000004.11:g.1807889A>G,NC_000004.12:g.1806162A>G,NM_000142.5:c.1948A>G,NP_000133.1:p.Lys650Glu
- Variant Type(s)
- missense_variant
- Evidence Items
- 4
Evidence Level Distribution
Level D: 4
Evidence Items
Showing CIViC evidence rows where gene = FGFR3 and variant = K650E.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Does Not Support | Resistance | Cancer | R3Mab | 3 |
| D | Functional | Supports | Gain of Function | 3 | ||
| D | Functional | Supports | Gain of Function | 3 | ||
| D | Functional | Supports | Gain of Function | 1 |