Variant Summary
- Also known as
- RS121913444,LEU861ARG
- HGVS
- NM_005228.4:c.2582T>G,NP_005219.2:p.Leu861Arg,NC_000007.13:g.55259524T>G,NC_000007.14:g.55191831T>G,ENST00000275493.7:c.2582T>G,ENSP00000275493.2:p.Leu861Arg
- Variant Type(s)
- missense_variant
- Evidence Items
- 1
Evidence Level Distribution
Level C: 1
Evidence Items
Showing CIViC evidence rows where gene = EGFR and variant = L861R.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Gefitinib | 3 |