CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 155 · Gene: RUNX1

Variant Summary

HGVS
—
Variant Type(s)
loss_of_function_variant,transcript_variant
Evidence Items
6

Evidence Level Distribution

Level B: 6

Evidence Items

Showing CIViC evidence rows where gene = RUNX1 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsResistanceAcute Myeloid LeukemiaCytarabine4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia3
BPrognosticSupportsPoor OutcomeAcute Lymphoblastic Leukemia3