CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

Mutation

CIViC ID: 157 · Gene: TET2

Variant Summary

HGVS
Variant Type(s)
gene_variant,loss_of_function_variant
Evidence Items
6

Evidence Level Distribution

Level B: 6

Evidence Items

Showing CIViC evidence rows where gene = TET2 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticDoes Not SupportAcute Myeloid Leukemia4
BPrognosticSupportsBetter OutcomeMyelodysplastic Syndrome4
BPrognosticSupportsBetter OutcomeAcute Myeloid Leukemia4
BPrognosticSupportsAcute Myeloid Leukemia4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4