CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/E374K

E374K

CIViC ID: 1648 · Gene: POLD1

Variant Summary

Also known as
GLU374LYS
HGVS
ENST00000440232.2:c.1120G>A
Variant Type(s)
missense_variant
Evidence Items
1

Evidence Level Distribution

Level C: 1

Evidence Items

Showing CIViC evidence rows where gene = POLD1 and variant = E374K.

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaPembrolizumab2