CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 1690 · Gene: RET

Variant Summary

HGVS
—
Variant Type(s)
—
Evidence Items
4

Evidence Level Distribution

Level A: 2Level B: 2

Evidence Items

Showing CIViC evidence rows where gene = RET and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
APredictiveSupportsSensitivity/ResponseMedullary Thyroid CarcinomaSelpercatinib4
APredictiveSupportsSensitivity/ResponseMedullary Thyroid CarcinomaSelpercatinib4
BPredictiveSupportsSensitivity/ResponseMedullary Thyroid CarcinomaSelpercatinib3
BPrognosticSupportsPoor OutcomeMedullary Thyroid Carcinoma3