CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Gain-of-function

Gain-of-function

CIViC ID: 1765 · Gene: EGFR

Variant Summary

Also known as
ACTIVATING MUTATION
HGVS
—
Variant Type(s)
—
Evidence Items
1

Evidence Level Distribution

Level B: 1

Evidence Items

Showing CIViC evidence rows where gene = EGFR and variant = Gain-of-function.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaGefitinib4