CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 177 · Gene: ASXL1

Variant Summary

HGVS
—
Variant Type(s)
protein_altering_variant
Evidence Items
6

Evidence Level Distribution

Level B: 6

Evidence Items

Showing CIViC evidence rows where gene = ASXL1 and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia5
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia4
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia3
BPrognosticSupportsPoor OutcomeMyelofibrosis3
BDiagnosticSupportsPositiveAcute Myeloid Leukemia3
BPrognosticSupportsPoor OutcomeAcute Myeloid Leukemia2