Variant Summary
- Also known as
- C.485G>T,CYS162PHE,RS397516444
- HGVS
- NM_000551.3:c.485G>T,NP_000542.1:p.Cys162Phe,NC_000003.11:g.10191492G>T,ENST00000256474.2:c.485G>T
- Variant Type(s)
- missense_variant
- Evidence Items
- 4
Evidence Level Distribution
Level C: 4
Evidence Items
Showing CIViC evidence rows where gene = VHL and variant = C162F (c.485G>T).
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 2 | |
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 2 | |
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 2 | |
| C | Predisposing | Supports | Uncertain Significance | Von Hippel-Lindau Disease | 1 |