CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Underexpression

Underexpression

CIViC ID: 179 · Gene: ATM

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
5

Evidence Level Distribution

Level B: 3Level D: 2

Evidence Items

Showing CIViC evidence rows where gene = ATM and variant = Underexpression.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseCancerKU-0060648,NU74415
DPredictiveSupportsSensitivity/ResponseGastric AdenocarcinomaOlaparib4
BPrognosticSupportsPoor OutcomeChronic Lymphocytic Leukemia3
BPrognosticSupportsPoor OutcomePancreatic Cancer2
BPredictiveSupportsSensitivity/ResponseStomach CancerOlaparib,Paclitaxel1