CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Amplification

Amplification

CIViC ID: 18 · Gene: CCND1

Variant Summary

HGVS
—
Variant Type(s)
transcript_amplification
Evidence Items
6

Evidence Level Distribution

Level B: 3Level D: 3

Evidence Items

Showing CIViC evidence rows where gene = CCND1 and variant = Amplification.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveDoes Not SupportSensitivity/ResponseOvarian CancerPalbociclib3
BPrognosticSupportsPoor OutcomeLung Non-small Cell Carcinoma3
BPredictiveDoes Not SupportResistanceBreast CancerTamoxifen3
BPredictiveSupportsSensitivity/ResponseSkin MelanomaCarboplatin,Paclitaxel,Sorafenib2
DPredictiveDoes Not SupportSensitivity/ResponseRenal Cell CarcinomaPalbociclib2
DPredictiveSupportsSensitivity/ResponseBreast CancerPalbociclib2