Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

CIViC Variants/Q195* (c.583C>T)

Q195* (c.583C>T)

CIViC ID: 1810 · Gene: VHL

Variant Summary

Also known as: C.583C>T,Q195X,GLN195TER,RS5030825
HGVS: NM_000551.3:c.583C>T,NP_000542.1:p.Gln195Ter,NC_000003.11:g.10191590C>T,ENST00000256474.2:c.583C>T
Variant Type(s): stop_gained
Evidence Items: 9

Evidence Level Distribution

Level C: 9

Evidence Items

Showing CIViC evidence rows where gene = VHL and variant = Q195* (c.583C>T).

Level	Type	Direction	Significance	Disease	Drugs	Rating
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		4
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		3
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		3
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		3
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		3
C	Predisposing	Supports	Uncertain Significance	Von Hippel-Lindau Disease		3
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		2
C	Predisposing	Supports	Predisposition	Von Hippel-Lindau Disease		2
C	Predisposing	Supports	Uncertain Significance	Von Hippel-Lindau Disease		1