Variant Summary
- Also known as
- C.208G>T,E70X,GLU70TER,RS5030802
- HGVS
- NM_000551.3:c.208G>T,NP_000542.1:p.Glu70Ter,NC_000003.11:g.10183739G>T,ENST00000256474.2:c.208G>T
- Variant Type(s)
- stop_gained
- Evidence Items
- 4
Evidence Level Distribution
Level C: 4
Evidence Items
Showing CIViC evidence rows where gene = VHL and variant = E70* (c.208G>T).
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 4 | |
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 3 | |
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 2 | |
| C | Predisposing | Supports | Predisposition | Von Hippel-Lindau Disease | 2 |