CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/L188V (c.562C>G)

L188V (c.562C>G)

CIViC ID: 1836 · Gene: VHL

Variant Summary

Also known as
C.562C>G,LEU188VAL,RS5030824
HGVS
NM_000551.3:c.562C>G,NP_000542.1:p.Leu188Val,NC_000003.11:g.10191569C>G,ENST00000256474.2:c.562C>G
Variant Type(s)
missense_variant
Evidence Items
2

Evidence Level Distribution

Level C: 2

Evidence Items

Showing CIViC evidence rows where gene = VHL and variant = L188V (c.562C>G).

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredisposingSupportsPredispositionVon Hippel-Lindau Disease3
CPredisposingSupportsPredispositionVon Hippel-Lindau Disease3