Variant Summary
- HGVS
- —
- Variant Type(s)
- transcript_variant
- Evidence Items
- 7
Evidence Level Distribution
Level B: 7
Evidence Items
Showing CIViC evidence rows where gene = DNMT3A and variant = Mutation.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Prognostic | Supports | Poor Outcome | Acute Myeloid Leukemia | 4 | |
| B | Prognostic | Supports | Poor Outcome | Acute Myeloid Leukemia | 4 | |
| B | Prognostic | Supports | Poor Outcome | T-cell Acute Lymphoblastic Leukemia | 4 | |
| B | Prognostic | Supports | Poor Outcome | Myelodysplastic Syndrome | 3 | |
| B | Predictive | Supports | Sensitivity/Response | Acute Myeloid Leukemia | Decitabine | 3 |
| B | Prognostic | Supports | Poor Outcome | Acute Myeloid Leukemia | 3 | |
| B | Predictive | Supports | Resistance | Cancer | Atezolizumab,Nivolumab,Pembrolizumab | 2 |