CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/P59fs (c.176delC)

P59fs (c.176delC)

CIViC ID: 1929 · Gene: VHL

Variant Summary

Also known as
PRO59FS,C.176DELC,P59RFS*8 (C.176DELC)
HGVS
ENST00000256474.2:c.176delC,NC_000003.11:g.10183707del,NM_000551.3:c.176del,NP_000542.1:p.Pro59ArgfsTer8
Variant Type(s)
frameshift_truncation,minus_1_frameshift_variant
Evidence Items
1

Evidence Level Distribution

Level C: 1

Evidence Items

Showing CIViC evidence rows where gene = VHL and variant = P59fs (c.176delC).

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredisposingSupportsPredispositionVon Hippel-Lindau Disease4