Variant Summary
- HGVS
- —
- Variant Type(s)
- transcript_ablation
- Evidence Items
- 10
Evidence Level Distribution
Level A: 2Level B: 8
Evidence Items
Showing CIViC evidence rows where gene = IKZF1 and variant = Deletion.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| A | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 5 | |
| A | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 5 | |
| B | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 4 | |
| B | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 4 | |
| B | Predictive | Supports | Sensitivity/Response | B-lymphoblastic Leukemia/lymphoma | Cytarabine,Daunorubicin,Imatinib,Methotrexate,Fludarabine | 4 |
| B | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 4 | |
| B | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 3 | |
| B | Prognostic | Supports | Poor Outcome | Acute Lymphoblastic Leukemia | 3 | |
| B | Prognostic | Supports | Poor Outcome | Acute Lymphoblastic Leukemia | 3 | |
| B | Prognostic | Supports | Poor Outcome | B-lymphoblastic Leukemia/lymphoma | 3 |