CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/P-Loop Mutation

P-Loop Mutation

CIViC ID: 2375 · Gene: ABL1

Variant Summary

HGVS
—
Variant Type(s)
—
Evidence Items
3

Evidence Level Distribution

Level B: 2Level C: 1

Evidence Items

Showing CIViC evidence rows where gene = ABL1 and variant = P-Loop Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveDoes Not SupportResistanceChronic Myeloid LeukemiaBosutinib3
BPredictiveDoes Not SupportResistanceChronic Myeloid LeukemiaBosutinib2
CPredictiveSupportsResistanceChronic Myeloid LeukemiaImatinib2