CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/DNA Binding Domain Mutation

DNA Binding Domain Mutation

CIViC ID: 242 · Gene: TP53

Variant Summary

HGVS
—
Variant Type(s)
DNA_binding_site
Evidence Items
2

Evidence Level Distribution

Level B: 2

Evidence Items

Showing CIViC evidence rows where gene = TP53 and variant = DNA Binding Domain Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPrognosticSupportsPoor OutcomeOral Squamous Cell Carcinoma4
BPredictiveSupportsResistanceBreast CancerTamoxifen3