Variant Summary
- Also known as
- GLN399ARG,RS25487
- HGVS
- NM_006297.2:c.1196A>G,NP_006288.2:p.Gln399Arg,NC_000019.9:g.44055726T>C,ENST00000262887.5:c.1196A>G
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level B: 2
Evidence Items
Showing CIViC evidence rows where gene = XRCC1 and variant = Q399R.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Prognostic | Supports | Better Outcome | Lung Non-small Cell Carcinoma | 4 | |
| B | Predictive | Supports | Sensitivity/Response | Cervical Cancer | Cisplatin,Carboplatin | 4 |