Variant Summary
- Also known as
- LYS751GLN
- HGVS
- NC_000019.9:g.45854919T>G
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level B: 2
Evidence Items
Showing CIViC evidence rows where gene = ERCC2 and variant = K751Q.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Resistance | Osteosarcoma | Cisplatin | 4 |
| B | Predictive | Supports | Sensitivity/Response | Lung Non-small Cell Carcinoma | Carboplatin,Paclitaxel | 3 |