CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Activating Mutation

Activating Mutation

CIViC ID: 2657 · Gene: ERBB2

Variant Summary

HGVS
—
Variant Type(s)
gene_variant,gain_of_function_variant
Evidence Items
1

Evidence Level Distribution

Level B: 1

Evidence Items

Showing CIViC evidence rows where gene = ERBB2 and variant = Activating Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveDoes Not SupportSensitivity/ResponseCancerAfatinib3