CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Fusion

Fusion

CIViC ID: 2660 · Gene: NUP214::ABL1

Variant Summary

Also known as
NUP214-ABL1
HGVS
—
Variant Type(s)
transcript_fusion
Evidence Items
5

Evidence Level Distribution

Level B: 1Level C: 3Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = NUP214::ABL1 and variant = Fusion.

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredictiveSupportsSensitivity/ResponseB-lymphoblastic Leukemia/lymphomaImatinib Mesylate4
BPrognosticSupportsBetter OutcomeB-lymphoblastic Leukemia/lymphoma3
CPredictiveSupportsSensitivity/ResponseB-lymphoblastic Leukemia/lymphoma, BCR-ABL1–likeDexamethasone,Dasatinib,Vincristine2
CDiagnosticSupportsPositiveB-lymphoblastic Leukemia/lymphoma, BCR-ABL1–like2
DPredictiveDoes Not SupportSensitivity/ResponseB-lymphoblastic Leukemia/lymphomaPonatinib,Nilotinib,Dasatinib,Imatinib2