CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Fusion

Fusion

CIViC ID: 2678 · Gene: SNX2::ABL1

Variant Summary

Also known as
SNX2-ABL1
HGVS
—
Variant Type(s)
transcript_fusion
Evidence Items
7

Evidence Level Distribution

Level C: 6Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = SNX2::ABL1 and variant = Fusion.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsResistanceB-lymphoblastic Leukemia/lymphomaImatinib,Dasatinib3
CDiagnosticSupportsPositiveB-lymphoblastic Leukemia/lymphoma, BCR-ABL1–like3
CDiagnosticSupportsPositiveB-lymphoblastic Leukemia/lymphoma, BCR-ABL1–like3
CPredictiveSupportsResistanceB-lymphoblastic Leukemia/lymphomaDasatinib2
CPredictiveSupportsReduced SensitivityB-lymphoblastic Leukemia/lymphomaImatinib1
CPrognosticSupportsPoor OutcomeB-lymphoblastic Leukemia/lymphoma1
CPrognosticSupportsPoor OutcomeB-lymphoblastic Leukemia/lymphoma1