CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Expression

Expression

CIViC ID: 268 · Gene: FGFR1

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
9

Evidence Level Distribution

Level B: 3Level D: 6

Evidence Items

Showing CIViC evidence rows where gene = FGFR1 and variant = Expression.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseLung CancerPonatinib4
DPredictiveSupportsSensitivity/ResponseSarcomaFexagratinib,Infigratinib,FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD1730743
DPredictiveSupportsSensitivity/ResponseHead And Neck Squamous Cell CarcinomaInfigratinib3
BPrognosticSupportsPoor OutcomeBreast Cancer2
DPredictiveSupportsSensitivity/ResponseGastric AdenocarcinomaInfigratinib2
DPredictiveSupportsSensitivity/ResponseBladder CarcinomaPD173074,Dovitinib2
DPredictiveSupportsSensitivity/ResponseColorectal CancerInfigratinib2
BPrognosticSupportsPoor OutcomeHead And Neck Squamous Cell Carcinoma2
BPrognosticSupportsPoor OutcomeHead And Neck Squamous Cell Carcinoma1