Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

CIViC Variants/Fusion

Fusion

CIViC ID: 2693 · Gene: v::ROS1

Variant Summary

Also known as: ROS1 Fusion,ROS1 Rearrangement
HGVS: —
Variant Type(s): transcript_fusion
Evidence Items: 8

Evidence Level Distribution

Level A: 6Level C: 1Level E: 1

Evidence Items

Showing CIViC evidence rows where gene = v::ROS1 and variant = Fusion.

Level	Type	Direction	Significance	Disease	Drugs	Rating
A	Predictive	Supports	Sensitivity/Response	Lung Non-small Cell Carcinoma	Entrectinib	5
A	Predictive	Supports	Sensitivity/Response	Lung Non-small Cell Carcinoma	Crizotinib	5
A	Predictive	Supports	Sensitivity/Response	Lung Non-small Cell Carcinoma	Crizotinib	4
A	Predictive	Supports	Sensitivity/Response	Lung Non-small Cell Carcinoma	Crizotinib	4
A	Predictive	Supports	Sensitivity/Response	Lung Non-small Cell Carcinoma	Crizotinib	3
C	Predictive	Supports	Sensitivity/Response	Bronchiolo-alveolar Adenocarcinoma	Crizotinib	3
A	Predictive	Supports	Sensitivity/Response	Lung Non-small Cell Carcinoma	Entrectinib	3
E	Predictive	Supports	Sensitivity/Response	Colorectal Adenocarcinoma	Crizotinib	2