CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Mutation

Mutation

CIViC ID: 275 · Gene: HRAS

Variant Summary

HGVS
—
Variant Type(s)
coding_transcript_variant
Evidence Items
3

Evidence Level Distribution

Level B: 2Level D: 1

Evidence Items

Showing CIViC evidence rows where gene = HRAS and variant = Mutation.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseCancerEverolimus,Binimetinib,Mirdametinib,Selumetinib,MTOR Kinase Inhibitor AZD80553
BPredictiveSupportsSensitivity/ResponseBladder Urothelial CarcinomaTipifarnib2
BPredictiveSupportsSensitivity/ResponseHead And Neck Squamous Cell CarcinomaTipifarnib2