CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Exon 20 Insertion

Exon 20 Insertion

CIViC ID: 2854 · Gene: ERBB2

Variant Summary

HGVS
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Variant Type(s)
—
Evidence Items
2

Evidence Level Distribution

Level A: 1Level B: 1

Evidence Items

Showing CIViC evidence rows where gene = ERBB2 and variant = Exon 20 Insertion.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaTrastuzumab Deruxtecan5
APredictiveSupportsSensitivity/ResponseLung Non-small Cell CarcinomaTrastuzumab Deruxtecan4