CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/N144S

N144S

CIViC ID: 2923 · Gene: PRPS1

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
3

Evidence Level Distribution

Level D: 3

Evidence Items

Showing CIViC evidence rows where gene = PRPS1 and variant = N144S.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsResistanceB-lymphoblastic Leukemia/lymphomaMercaptopurine,Thioguanine4
DPredictiveDoes Not SupportResistanceB-lymphoblastic Leukemia/lymphomaMethotrexate,Asparaginase,Daunorubicin3
DPredictiveSupportsSensitivity/ResponseB-lymphoblastic Leukemia/lymphomaCytarabine2