Variant Summary
- HGVS
- —
- Variant Type(s)
- transcript_amplification
- Evidence Items
- 3
Evidence Level Distribution
Level A: 1Level D: 2
Evidence Items
Showing CIViC evidence rows where gene = MYCN and variant = Amplification.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| A | Prognostic | Supports | Poor Outcome | Neuroblastoma | 4 | |
| D | Predictive | Supports | Sensitivity/Response | Neuroblastoma | JQ1,Panobinostat | 3 |
| D | Predictive | Supports | Sensitivity/Response | Neuroblastoma | FACT Complex-targeting Curaxin CBL0137 | 3 |