CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Fusion

Fusion

CIViC ID: 2992 · Gene: TPM3::NTRK1

Variant Summary

Also known as
TPM3-NTRK1
HGVS
—
Variant Type(s)
transcript_fusion
Evidence Items
8

Evidence Level Distribution

Level A: 1Level C: 5Level D: 2

Evidence Items

Showing CIViC evidence rows where gene = TPM3::NTRK1 and variant = Fusion.

LevelTypeDirectionSignificanceDiseaseDrugsRating
APredictiveSupportsSensitivity/ResponseSolid TumorLarotrectinib Regimen5
CPredictiveSupportsSensitivity/ResponseSarcomaLarotrectinib4
CPredictiveSupportsSensitivity/ResponseLung CarcinomaLarotrectinib3
CPredictiveSupportsSensitivity/ResponseSpindle Cell SarcomaLarotrectinib3
CPredictiveSupportsSensitivity/ResponsePapillary Thyroid CarcinomaLarotrectinib3
DPredictiveSupportsSensitivity/ResponseCancerEntrectinib2
DPredictiveSupportsSensitivity/ResponseColorectal CancerLarotrectinib,Lestaurtinib2
CPredictiveSupportsSensitivity/ResponseMyofibromaEntrectinib1