Variant Summary
- HGVS
- —
- Variant Type(s)
- loss_of_function_variant,gene_variant
- Evidence Items
- 2
Evidence Level Distribution
Level B: 2
Evidence Items
Showing CIViC evidence rows where gene = PTCH1 and variant = Mutation.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Predictive | Supports | Sensitivity/Response | Medulloblastoma | Sonidegib | 4 |
| B | Predictive | Supports | Sensitivity/Response | Cancer | Vismodegib | 1 |